Trilostane Dose For Dogs

Trilostane also commonly known as vetoryl is a medication used commonly in the treatment of cushing s disease in dogs.

Trilostane dose for dogs.

Vetoryl trilostane capsules dosage and administration. While many vets have used trilostane for years the fda has also approved it for the treatment of cushing s in. Twenty three dogs with pdh had their dose or frequency of trilostane administration increased during the study. Trilostane works in dogs by inhibiting cortisol production in the adrenal gland.

Always provide the client information sheet with prescription. How trilostane works for dogs. It is a prescription medication and requires you to visit the vet before use. This dog responded to trilostane discontinuation and supportive care.

Indicated for the treatment of pituitary dependent hyperadrenocorticism in dogs and the treatment of hyperadrenocorticism due to adrenocortical tumor in dogs. The starting dose for the treatment of hyperadrenocorticism in dogs is 1 0 3 0 mg lb 2 2 6 7 mg kg once a day. Vetoryl trilostane approved by the fda in 2008 is the only drug approved to treat both pituitary and adrenal dependent cushing s in dogs. Cushing s disease is a fairly rare endocrine diseases of dogs.

Vetoryl capsules are indicated for the treatment of hyperadrenocorticism due to adrenocortical tumor in dogs. Trilostane affects the imbalance of the hormone cortisol which is released by the adrenal glands. Mean trilostane dosage at 1 year reevaluation in dogs with a good response was 1 7 mg kg 0 8 mg lb twice daily or 1 1 mg kg 3 times daily. Reducing the dose and slowly increasing to the recommended schedule may reduce the side effects.

Trilostane vetoryl is indicated for the treatment of pituitary dependant hyperadrenocorticism and treatment of hyperadrenocorticism due to adrenocortical tumors in dogs. The treatment helps balance the hormone levels to provide relief and control cushing s over the long term. Always follow the dosage instructions from your veterinarian. However side effects can include lethargy vomiting diarrhea and lack of appetite during the first few days of therapy.

Two dogs developed hypoadrenocorticism during the study. These two dogs had clinical signs consistent with hypoadrenocorticism lethargy anorexia collapse and post acth cortisol levels 0 3 µg dl. Cushing s disease and vetoryl trilostane cushing s disease is a uncommon condition in older dogs often mistaken for the aging process itself. Vetoryl capsules trilostane 120 mg.

Yet cushing s disease is treatable and that treatment can result in a longer more comfortable life for the dog and its owner.